产品货号：
GS4477
中文名称：
重组小鼠IL-11
英文名称：
Recombinant Murine Interleukin-11
产品规格：
2μg
发货周期：
1～3天
产品价格：
询价
分子量：Approximately 19.1kDa,a single non-glycosylated polypeptide chain containing 179 amino acids.
储存条件：冷冻（-20℃）
概述
Interleukin-11(IL-11)is encoded by the IL11 gene.IL-11 is a multifunctional cytokine first isolated from bone marrow-derived stromal cells.IL-11 receptor activation requires formation of a complex of two IL-11 molecules with two molecules of the ligand-binding IL-11 Rα subunit and two molecules of the expressed cell signaling β subunit,gp130.IL-11 is a member of the IL-6 superfamily,distinguished based on their use of the common co-receptor gp130.IL-11 can directly stimulate the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells,and induce megakaryocyte maturation resulting in increased platelet production.Mature murine IL-11 shares 88%amino acid sequence identity with human IL-11.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
相关搜索：重组小鼠IL-11，IL-11, Murine，Recombinant Murine Interleukin-11
储存条件：冷冻（-20℃）
概述
Interleukin-11(IL-11)is encoded by the IL11 gene.IL-11 is a multifunctional cytokine first isolated from bone marrow-derived stromal cells.IL-11 receptor activation requires formation of a complex of two IL-11 molecules with two molecules of the ligand-binding IL-11 Rα subunit and two molecules of the expressed cell signaling β subunit,gp130.IL-11 is a member of the IL-6 superfamily,distinguished based on their use of the common co-receptor gp130.IL-11 can directly stimulate the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells,and induce megakaryocyte maturation resulting in increased platelet production.Mature murine IL-11 shares 88%amino acid sequence identity with human IL-11.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 | ＞97%by SDS-PAGE and HPLC analyses. |
| 来源 | Escherichia coli. |
| 生物活性 | Fully biologically active when compared to standard.The ED50 as determined by a cell proliferation assay using murine T11 cells is less than 2ng/ml,corresponding to a specific activity of>5.0×105 IU/mg. |
| 成分 | Lyophilized from a 0.2μmfiltered solution in PBS,pH 7.4. |
| 内毒素 | Less than 1 EU/μg of rMuIL-11 as determined by LAL method. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions. |
| 氨基酸序列 | MPGPPAGSPR VSSDPRADLD SAVLLTRSLL ADTRQLAAQM RDKFPADGDHSLDSLPTLAM SAGTLGSLQL PGVLTRLRVD LMSYLRHVQW LRRAGGPSLKTLEPELGALQ ARLERLLRRL QLLMSRLALP QAAPDQPVIP LGPPASAWGSIRAAHAILGG LHLTLDWAVR GLLLLKTRL |
相关搜索：重组小鼠IL-11，IL-11, Murine，Recombinant Murine Interleukin-11